Apple Silicon is now officially supported for installations in /opt/homebrew. formulae.brew.sh formula pages indicate for which platforms bottles (binary packages) are provided and therefore whether they are supported by Homebrew. Homebrew doesn’t (yet) provide bottles for all packages on Apple Silicon that we do on Intel x8664 but we welcome your help in doing so. Rosetta 2 on Apple Silicon still provides support for Intel x8664 in /usr/local.