Scientific Applications under Mojave Update 6
Whilst there are many sites that track the compatibility on common desktop applications, it is often difficult to find out information about scientific applications. Based on the number of page views on the lists for High Sierra, Sierra, El Capitan and Yosemite it is apparently a useful resource.
Apple has said that macOS 10.14 (Mojave) will run on every Mac released from 2012 onwards. Always a good idea to have a Time machine backup when undertaking a major update like this.
Much like prior versions of Mac OS, you can easily create a bootable install drive for MacOS Mojave 10.14. The initial installer is small (15 MB) but after the main installer has successfully downloaded (5GB+), when you are prompted to start the installation process, click Cancel, and the installer will be in the /Applications folder (Install macOS Mojave.app). You must make a copy of this to another location; otherwise if you launch the installer and it completes the Mojave update, it'll be deleted. I found installing or updating to macOS Mojave takes about 45 - 60 minutes depending on the age of the machine.
I’ll update the list regularly and please feel free to send in information.
Amsterdam Modeling Suite has Mojave support, more details soon.
Applescript, the security changes in Mojave have some significant impacts that are described in detail here, particularly to scripting additions..
Avogadro version 1.2.0 no issues
BBEdit have a comprehensive list of compatibility notes for each application and versions https://www.barebones.com/support/new-os.html. BBEdit 12.1.6 has just been released which bring full Mojave compatibility.
ChemDoodle all seems fine no issues reported
ChemDoodle3D all seems fine no issues reported
ChemDraw as a policy they do not test until after new operating systems have been released, will check back later. A user replied "I am on ChemDraw Pro 18.104.22.168 and I have found no compatibility issues on Mojave.".
Chimera buttons not being shown until the windows containing them are resized. "Just an update that we’ve fixed the button issue in Chimera on Mojave" 1.13.1 candidate release (and recent 1.14 daily builds) working on Mojave
ChimeraX No issues reported.
ChirysView "As far as we know, there are no issues with our products and Mojave".
Cresset No issues to date, more detailed testing underway.
CrystalMaker "CrystalMaker X works beautifully with Mojave. We’re a full 64-bit app with sandboxing and code signing. Our forthcoming 10.4 update (next week or so) will include a “Dark Mode” option".
DataWarrior no issues to date
Findings no issues
iBabel no issues to date
iRaspa no issues
MarvinSketch latest version no issues, earlier versions may require the old Apple supplied JDK to be reinstalled
MarvinView no issues
Microsoft have already announced compatibility notes.
Word, Excel, PowerPoint, Outlook, OneDrive, Skype for Business, and OneNote will install and run on macOS 10.14 Mojave. Microsoft fully supports Office 2016, Office 2019 and Office 365 for Mac on 10.14 Mojave when you have the following Office updates installed:
Office 365/2019 - Build 16.17.0 or later
Office 2016 - Build 16.16.2 or later
Skype for Business 16.21.65 or later
Mnova lite no issues reported
Molecular Materials and Informatics have just released an update for the Molecular notebook app
MOE There seem to be no problems running MOE 2018.01 or higher on MacOS 10.14.
MolSoft We have not had any reported issues about running ICM-Pro or ICM-Chemist-Pro on Mac OSX 10.14 Mojave.
O "It runs on my laptop without problem and I’ve not heard any news from users so I don’t think there are any issues at the moment."
Openbabel no reported issues
PyCharm only very minor issues
PyMOL "Although Mojave was just released, all of our automated and QA tests do not show anything out of the ordinary. While it's probably still too early to declare official support, we haven't encountered anything that suggests users should worry about upgrading with regards to the PyMOL application".
RDKit no reported issues
Schrodinger suites are not yet officially supported on Mojave. Tests are ongoing, and we're hoping to officially support that platform in our next release (2018-4).
SeeSAR "0 issues with Mojave at our end".
StarDrop Our initial tests suggest that everything is working as expected.
TextWrangler is not compatible with Mojave. It has been sunsetted, and is now part of BBEdit.
Vortex no issues reported.
xQuartz I've only done limited testing but all OK for me.
Updated 30 October 2018