Macs in Chemistry

Insanely Great Science

Mobile maleria immunoassay and more


An interesting paper from George Whitesides et al “Universal mobile electrochemical detector designed for use in resource-limited applications” in PNAS DOI. It describes an inexpensive, handheld device that couples the most common forms of electrochemical analysis directly to “the cloud” using a mobile phone.

Several electroanalytical techniques (chronoamperometry, cyclic voltammetry, differential pulse voltammetry, square wave voltammetry, and potentiometry) are described and demonstrated.

Four applications demonstrate the analytical performance of the device: these involve the detection of (i) glucose in the blood for personal health, (ii) trace heavy metals (lead, cadmium, and zinc) in water for in-field environmental monitoring, (iii) sodium in urine for clinical analysis, and (iv) a malarial antigen (Plasmodium falciparum histidine-rich protein 2) for clinical research.

Full technical details are included in the supporting information.

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