OpenEye have announced the release of OpenEye Toolkits v2015.October. These libraries include the usual support for C++, Python, C# and Java.

New Features

• FastROCS TK was added to the OpenEye toolkits collection
• Molecule reading performance improvement in OEChem TK
• The capabilities of the OEBio-Fragment Network have been expanded
• 213 new ring templates have been added to the OEChem TK built-in ring dictionary

The full release notes give more details

In particular note the 2015.Oct release is the last to support Mac OSX 10.8 so time to upgrade if you have not already done so.