The OpenPhacts API has been updated to include two new data sets and the corresponding API calls.

1) DisGeNet target-disease associations These API calls use URIs inputs that correspond to either diseases or targets (proteins or genes). The disease identifiers correspond to UMLS CUIs, Mesh ids or ConceptWiki and can use several namespaces, e.g. http://linkedlifedata.com/resource/umls/id/C0004238, http://purl.bioontology.org/ontology/MSH/D001281, or http://www.conceptwiki.org/concept/index/095cb66f-76ef-41b5-a8ae-c39352e6007e

2) neXtProt nanopublications for tissue expression (PREVIEW mode) These API calls use URIs that correspond to either tissues or targets. The tissue identifiers correspond to the Caloha tissue ontology from neXtProt. These identifiers can use either the namespace from the neXtProt database (e.g. http://www.nextprot.org/db/term/TS-0564, will be operational next week) or the Caloha ontology (ftp://ftp.nextprot.org/pub/currentrelease/controlledvocabularies/caloha.obo#TS-0564, operational now).

To reduce the barriers to drug discovery in industry, academia and for small businesses, the Open PHACTS Discovery Platform provides tools and services to interact with multiple integrated and publicly available data sources. To integrate this data, extensive cross-referencing of scientific concepts is needed across all databases.