SeeSAR has been updated to 5.2, with loads of features that many people had on their wish list

1. ReCore-improvements: auto-avoid clashes and duplicates; load and install the index from within SeeSAR
2. Simplify binding mode visualization, e.g. by hiding all amino acids not interacting with your compound
3. Color coded protein surface: by either element, depth of the pocket, hydrophilicity
4. For more details and all improvements see: http://www.biosolveit.de/SeeSAR/changes.html

SeeSAR is a software tool for interactive, visual compound prioritization as well as compound evolution. Structure-based design work ideally supports a multi-parameter optimization to maximize the likelihood of success, rather than affinity alone. Having the relevant parameters at hand in combination with real-time visual computer assistance in 3D is one of the strengths of SeeSAR.