FITTED has been updated
FITTED has been updated to 2.6.1 and is available for download.
FITTED is a suite of programs to dock flexible ligands into flexible proteins. This software relies on a genetic algorithm to account for flexibility of the two molecules and location of water molecules, and on a novel application of a switching function to retain or displace water molecules and to form potential covalent bonds with the protein side-chains.
- FITTED is a suite of programs (FITTED, ProCESS and SMART)
- Fully automated and flexible docking program
- Uses an evolutionary algorithm
- Semi-flexible protein docking with flexible waters
- Has the ability to consider water molecules displaceable
- Different docking modes available: Dock, Filter, SAR, VS and Score
- Runs on Linux, Mac and Windows
- Accuracy and speed