Tip for improving ChemBioDraw printing
I recently received this tip for improving the quality of printing from ChemBioDraw that I thought I could share.
What is happening is that printing from an Intel Mac with ChemDraw results in a different appearance than printing from a PowerPC Mac. Apple used to allow Postscript to be embedded in old fashioned QuickDraw printing so that ChemDraw could make very nice output to a Postscript printer. Unfortunately, they dropped that functionality during the Intel transition, as they've given people enough time to move to Quartz printing.
So, now if you use ChemDraw 11 to print, you will see that there is a lack of fine detail, the positioning of characters is not as refined as it could be, and the splines in the Bio Draw objects just look awful. You can print to PDF as see what I mean. And the PDF will be really bulky if there are BioDraw splines in it, or free hand pen tool shapes.
The work around is to not print from ChemDraw but to save as an EPS file and use OS X Preview to print that, but you will run into trouble if you use unusual (not Times, Helvetica, etc.) fonts.
In the image below you can see the difference in quality, the left-hand image was printed directly from ChemBioDraw the right-hand image was the same file first saved in EPS (Encapsulted postscript) format. As you can see the curved line is much cleaner.
There is a review of ChemBioDraw here