At long last ChemDraw for Mac has been updated. The latest version now supports Mac OS X 10.10 (Yosemite) and supports the retina display.

Whereas in the past we had Std, Pro and Ultra we now have Prime and Professional and cross grades are available.

Update

A reader just sent me the official ChemDraw 15 feature chart

The ability to search SciFinder is now available in ChemDraw Professional Mac version, and the only differences are lack of OLE editing, and the absence of the pKa LogP LogS calculations.