The 2022.02 release of Chemical Computing Group's Molecular Operating Environment (MOE) software includes a variety of new features, including support for Apple Silicon!

This update also includes

• Browser-based Combinatorial Library Enumeration with on-the-fly reagent search and library generation

• MOEsaic Docking calculations with real-time visualization of results

• scFv and custom antibody homology models

• GPU-accelerated protein modeling and protein-protein docking

• Hydrogen Mass Repartitioning for accelerating MD and Thermodynamic Integration

• Database Viewer SNFG carbohydrate display, graphic objects, and enhanced plotting

If you want to read more about the performance gains using MOE on an M1 Mac have a look at this page https://www.macinchem.org/reviews/MacBooks/moe.php.