RDkit has been updated .
If you used home-brew to install RDkit as described here updating is very simple
brew update brew upgrade rdkit
You can check which version you have installed using
MacPro> python Python 2.7.11 (default, Dec 23 2015, 16:11:50) [GCC 4.2.1 Compatible Apple LLVM 7.0.2 (clang-700.1.81)] on darwin Type "help", "copyright", "credits" or "license" for more information. >>> from rdkit import rdBase >>> print rdBase.rdkitVersion 2016.03.1 >>>