A Noel O'Blog post giving a few useful tips for writing scripts or plugins for Vortex https://baoilleach.blogspot.com/2022/04/threading-time-through-vortex.html.

Vortex (a chemical spreadsheet/visualisation software from Dotmatics) has a plugin system built around Jython. Simply drop a .vpy file into a specific scripts folder, and a menu item immediately appears in the application. Here are some notes on using this to communicate with a webserver.

The tutorials page on this site also includes many examples of Vortex scripts.